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114446-55-8

  • Product Name:(S)-1-(2-BROMOPHENYL)ETHANOL
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Product Details

Purity:99%

High Quality 114446-55-8 (S)-1-(2-BROMOPHENYL)ETHANOL with Cheap Price

  • Molecular Formula:C8H9BrO
  • Molecular Weight:201.063
  • Appearance/Colour:off-white to light yellow crystalline powder 
  • Vapor Pressure:0.0172mmHg at 25°C 
  • Melting Point:56-58 °C(lit.) 
  • Refractive Index:1.572 
  • Boiling Point:243.5 °C at 760 mmHg 
  • PKA:14.01±0.20(Predicted) 
  • Flash Point:113.3 °C 
  • PSA：20.23000 
  • Density:1.47 g/cm3 
  • LogP:2.50240 

(S)-1-(2-Bromophenyl)ethanol(Cas 114446-55-8) Usage

Chemical Properties

off-white to light yellow crystalline powder

Uses

Used in the synthesis of chiral boronic acids, which serve as reagents for enantiomeric purity determination of diols by H-NMR.

InChI:InChI=1/C8H9BrO/c1-6(10)7-4-2-3-5-8(7)9/h2-6,10H,1H3/t6-/m0/s1

114446-55-8 Relevant articles

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A highly efficient heterogeneous asymmet...

Manganese-Catalyzed Enantioselective Hydrogenation of Simple Ketones Using an Imidazole-Based Chiral PNN Tridentate Ligand

Chen, Jiachen,Hou, Huacui,Ling, Fei,Nian, Sanfei,Wu, Feifei,Xu, Min,Yi, Xiao,Zhong, Weihui

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Efficient Heterogeneous Asymmetric Transfer Hydrogenation of Ketones Using Highly Recyclable and Accessible Silica-Immobilized Ru-TsDPEN Catalysts

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(Matrix presented) Chiral Ru-TsDPEN [N-(...

Asymmetric hydrogenation of aromatic ketones by chiral (1S,2S)-DPEN-Ru(II)Cl2(TPP)2 encapsulated in SBA-16

Liu, Jianhong,Fan, Binbin,Liang, Dong,Shi, Xiufeng,Li, Ruifeng,Chen, Hua

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Chiral complex (1S,2S)-DPEN-RuCl2(TPP)2 ...

Fine-tuning of the substrate binding mode to enhance the catalytic efficiency of an: Ortho -haloacetophenone-specific carbonyl reductase

Li, Aipeng,Li, Xue,Pang, Wei,Tian, Qing,Wang, Ting,Zhang, Lianbing

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The asymmetric transfer hydrogenation (A...

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114446-55-8 Process route

2,2,2-Trifluoroacetophenone
434-45-7

2,2,2-Trifluoroacetophenone

(1R)-1-(2-bromophenyl)ethan-1-ol
5411-56-3,114446-55-8,118375-26-1,76116-20-6

(1R)-1-(2-bromophenyl)ethan-1-ol

S(+)-1-phenyl-2,2,2-trifluoroethanol
340-06-7

S(+)-1-phenyl-2,2,2-trifluoroethanol

Conditions
Conditions Yield
With ethanol; NADH; In aq. buffer; at 35 ℃; for 15h; pH=7; stereoselective reaction; Microbiological reaction; Enzymatic reaction;
32.3 % ee
1-(2-bromophenyl)ethanol
5411-56-3

1-(2-bromophenyl)ethanol

2-bromophenyl methyl ketone
2142-69-0

2-bromophenyl methyl ketone

(1S)-1-(2-bromophenyl)ethanol
5411-56-3,76116-20-6,118375-26-1,114446-55-8

(1S)-1-(2-bromophenyl)ethanol

(1R)-1-(2-bromophenyl)ethan-1-ol
5411-56-3,114446-55-8,118375-26-1,76116-20-6

(1R)-1-(2-bromophenyl)ethan-1-ol

Conditions
Conditions Yield
With sodium hydrogencarbonate; sodium bromide; chiral 4,1'-dinaphthyl-3,2'-cyclo[C(Me)2-N(oxyl)-C(Me)2]; In dichloromethane; water; at -15 ℃; for 1.5h; Title compound not separated from byproducts; Electrolysis;
54%
1-(2-bromophenyl)ethanol; With N,N'-bis(salicylidene)-1,2-cyclohexanediaminomanganese(III) chloride; potassium acetate; In dichloromethane; water; for 0.0833333h;
With N-Bromosuccinimide; In dichloromethane; water; at 20 ℃; for 4h; enantioselective reaction; Kinetics;
85 % ee

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